副研究员、重庆大学硕士生导师

长期深耕肿瘤精准诊疗与分子病理技术领域，专注于肿瘤分子分型、免疫治疗标志物挖掘及智慧病理体系建设。主持国家博士后基金（已结题）、两项省部级项目（在研一项）、一项区级项目（在研），以第一/共同第一作者在Cell Death & Disease（IF=9.6）、Oncogene（IF=7.3）、Genes & Diseases（IF=9.4）等国际权威期刊发表高水平 SCI 8 篇论文，荣获得2019年度黑龙江省医药卫生科学技术奖二等奖、2025年度全国博士后创新创业大赛铜奖。

（一）主要学术论文（第一 / 共同第一作者）

[1]Zhangxiang Zhao#, Wenbin Zhou#,Yue Han, Fuduan Peng, Ruiping Wang,Ruihan Yu,Chengyu Wang,Haihai Liang, Zheng Guo*,Yunyan Gu*. EMT-Regulome: a database for EMT-related regulatory interactions, motifs and network. Cell Death & Disease. 2017 Jun 15;8(6):e2872. 第一作者，IF：9.6

[2]Wenbin Zhou#, Zhangxiang Zhao#, Ruiping Wang, Yue Han, Chengyu Wang, Fan Yang, Ya Han, Haihai Liang, Lishuang Qi, Chenguang Wang, Zheng Guo*,Yunyan Gu*.Identification of driver copy number alterations in diverse cancer types and application in drug repositioning. Molecular oncology. 2017 Oct;11(10):1459-1474.(Cover Image) 共同第一作者，IF：7.4

[3]TingtingChen#, Zhangxiang Zhao#, BoChen, YuquanWang, FanYang, ChengyuWang, QiDong, Yaoyao Liu,HaihaiLiang, Wenyuan Zhao, Lishuang Qi,Yan Xu*,Yunyan Gu*. An individualized transcriptional signature to predict the epithelial-mesenchymal transition based on relative expression ordering. Aging (Albany NY). 2020 Jul 8;12(13):13172-13186. 共同第一作者，IF：6.6

[4]Zhangxiang Zhao#, YingYing Guo#, Yaoyao Liu#, Lichun Sun, Bo Chen, Chengyu Wang, Tingting Chen, Yuquan Wang, Yawei Li, Qi Dong, Liqiang Ai, Ran Wang, Yunyan Gu*, Xia Li*. Individualized lncRNA differential expression profile reveals heterogeneity of breast cancer. Oncogene. 2021 Jul;40(27):4604-4614. 第一作者，IF：7.3

[5]Yawei Li#, Zhangxiang Zhao#, Liqiang Ai, Yuquan Wang, Kaidong Liu, Bo Chen, Tingting Chen, Shuping Zhuang, Huanhuan Xu, Min Zou,Yunyan Gu*,Xia Li*. Discovering a qualitative transcriptional signature of homologous recombination defectiveness for prostate cancer. iScience. 2021 Sep 17;24(10):103135. 共同第一作者，IF：4.1

[6]Zhangxiang Zhao, Tongzhu Jin, Bo Chen, Qi Dong, Mingyue Liu, Jiayu Guo, Xiaoying Song, Yawei Li, Tingting Chen, Huiming Han, Haihai Liang, Yunyan Gu. Multi-omics integration analysis unveils heterogeneity in breast cancer at the individual level. Cell Cycle. 2023 Nov 16. 22(20): 2229–2244. DOI:10.1080/15384101.2023.2281816第一作者，IF：3.4

[7]Zhangxiang Zhao#, Yuquan Wang#, Zixin Jin, Huiming Han, Bo Chen, Mingyue Liu, Kaidong Liu, Shuping Zhuang, Haihai Liang, Yunyan Gu. Alternative splicing of immune-related genes identifies breast cancer subtypes with differential immune cell infiltration. Genes & Diseases, 2024; 2(12); 101349. DOI:10.1016/j.gendis.2024.101349. 第一作者，IF：9.4

[8]Mingyue Liu#, Zhangxiang Zhao#, Chengyu Wang, Shaocong Sang, Yanrui Cui, Chen Lv, Xiuqi Yang, Nan Zhang, Kai Xiong, Bo Chen, Qi Dong, Kaidong Liu, Yunyan Gu. Harnessing genetic interactions for prediction of immune checkpoint inhibitors response signature in cancer cells. Cancer Lett. 2024 Jul 10:594:216991. doi: 10.1016/j.canlet.2024.216991. 共同第一作者，IF：10.1

（二）荣誉奖项

l2019 年度 黑龙江省医药卫生科学技术奖二等奖（核心完成人）

l2025 年度 全国博士后创新创业大赛铜奖（项目负责人）